Head shot of Dr Nickk Cunniffee

Hosted in partnership with Brett Drummond from MStranslate, we are joined by Dr Nick Cunniffe, a leading clinical lecturer in neurology at the University of Cambridge, to discuss: Remyelination—the ability to repair damage in MS—which is widely viewed as the next major step forward in the treatment of the disease.

Video Summary

  • Duration: 1 hour
  • The Science of Repair: Discover how remyelination works and why our natural ability to repair myelin declines as we age.
  • The CCMR2 Trial Explained: Learn about the methodology and biological results of testing Metformin and Clemastine as a combination therapy.
  • A “Proof of Concept”: Why these results are a significant milestone for MS research, even if these specific drugs aren’t recommended for clinical use yet.
  • The Future of Treatment: Projected timeframes and factors involved with advancing remyelination strategies.  Insights into the “triple therapy” utopia of the future: combining immune therapies, neuroprotection, and remyelination.
  • Lifestyle & Research: A look at how exercise and other non-pharmacological factors play into nerve health and repair.

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